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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f8b28e2a4f18e9b3fa54e4e3fbcd505f3a21c6122adfb9c35a86f8db96af2d' 
  AND token = '11cgYNjIEHi9gSHS/7KRuvw3pRZ6uqPehp0yXXbvp8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}