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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e2c78bd22f6701d22119fb75489864a23b038a81017bad0d4712cfc6dfc2021' 
  AND token = 'V8gh10IY1TKdqL+02gmcZgao6Jafil//y8Rn9Y9E3us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}