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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2199aabeedbe481a3ed4e66792bc18996d8bcd0aaa239c5694bf3122ed869da' 
  AND token = 'O90jCnxPM3W3Q2R+sHiVk1vc1RbMa9LRSGLQa8ua0/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}