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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c666a6219e03d96b5a780f952943043240a181346cf1d25472a2454b1a9eff85' 
  AND token = '0S04v56iDvlo/jbeO2a/J5/PrI3WGzp2GPXTjeDkjfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}