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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '894d7d70e6d831690554131fee27132ac8cfa8d39ce7457784381f59aaf93799' 
  AND token = '7fB+F3lOIoQ41/uMMO28y8mZA3LYIaqJ17lvNRAilzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}