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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc2080a7ba7eeb90625bf1efff5e948f8c0d89b2d1b0853035a91a03d7c34292' 
  AND token = 'bIaoRFJ6cTx4mAdOvAKPrEBWQhyvg6P7/6OPyppK2IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}