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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8464cc72def9f5a78a3ec577268179b32ff37023e31965d735fc1c8b133bf3b1' 
  AND token = 'OaZh3Ho4GQ4FrB0kBv1xupPSa5WIxMTzYYD58Ka3hmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}