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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '325ba088a0be5dacb7b32ac4d121e072329853d95a0b249850cc90c4336d2d07' 
  AND token = 'LaCKz2zmyV1Qspgjt+fGkK5H5As74azkGSwZNTWekd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}