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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3878ba57cba1b793807a2ded9f238d3fd6dc6e4101e200b9caa34370b661e6a0' 
  AND token = 'aV46ardxNvr98cQLVXKamTO7nWKTNAI9ejMcJtecJM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}