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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4416e1e75807475e5b194f4325e798dcd9acbabeac1355c88cf808210e6f1d44' 
  AND token = 'cHDgiQId7+gHu2edaCRr1mrh8Kzm7xlbkJmBu90OG64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}