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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b11b3b0ce47336aa419333e296a5b5b29f8568d05c3d87af3adfbcb4f631450' 
  AND token = 'YTxR1lQS1rZQ67RY9tqTdunsS3dWqMHl/TlhsSvaONs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}