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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ed83372bdc83faf94d7409f928e515dc7008e280848b47076f3dee731a74ed' 
  AND token = '9GV2dljm8NKcQQMUhUl1k6gDfmdYWZVfX6ZXYyXjWfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}