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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61887d31e5b45e9a5a9d5e888994093c8c48238d7948d81ca5066f332d1ebb61' 
  AND token = 'ittYpxss28OyvrQd/YFw9SVmAtNe8q1N4yPmUiVAvXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}