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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d2c4c0919f6b246620a255bad78d5bb643185921da892ac3ac4467a3d79d894' 
  AND token = 'saqsBHgqrb82HyqT3EW3jmI89XVEnMPcyeOnNv+1ru4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}