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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6026af840c28b53185d6f76b117bed677dfac281349c489d669b4d847fe198f' 
  AND token = 'H7YBVHg6mH5pq1sxy8G2SefSbXSwoHE0TdgVc5+Z6Ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}