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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dab4ff6f16711b32c3978629fd4445b5d71429f53b6894381f027fa97c69087' 
  AND token = 'prZpJlLneF9jmo0mW4f+qt3KkX4qLF3nirkW7nshJ0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}