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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de4db588c8b21a730cce12cbbf3f81ab739357b054d4a76a4013fc89da0e36bf' 
  AND token = 'kYf74vYx/ewwhcKiMvjU3Mi8/SaUIutx6yxO40QTaSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}