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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e08b83bdc97fca5282b4d77424b893021b4b42c8895a44d7d67e93e58b2ba00c' 
  AND token = 'QyrvSnSShpKSvTDKqBcCc6m/o9h48h5Wc6t1GJUB8SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}