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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '723ec158500d22b214c8b45cce9c54ae178382522eb155230e97499c6ebff3ab' 
  AND token = 'yH8ymGlCnfRhK8X4raxvB9ceRAbKL6RLJbQW/yT8uJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}