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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d01125ece4d002d60693e358dda19199d5dc5fb79eded7ec45a5956c148f3e' 
  AND token = '88WzC1qpoZlnCDHyq+mtgSI0irdLiA1Ii5Ro7sZWC6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}