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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7906aaffb95795a7533a39536e0d63636e24d8c6b1f79a518d3dfa4f685db316' 
  AND token = 'HZr1WAEQqm3gOOGGL2Q+VbNHN+U3L0Ah4aD8tHhT268=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}