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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49657f219b0a052a14f03a7a9ddfdab276fb86b1f29437de4bd18eee4e91911' 
  AND token = 'tt/hAUzNgoY4ug6dm5v1ebRODL0VixJ2pcjHXbzSPpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}