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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54bd87f69d9c77cb1de078751cb710809741b0a81b19fdf824e22649886556c1' 
  AND token = 'ZsVL3qDTA45IqeM3C0QuMzkORyJTtD37YNFb5ThAASc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}