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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c44b58c3ce6d684d0819231f7157cc5d6102bd1679d73001286cf245b2857f0e' 
  AND token = 'zE3vr3zEtv0JZnPZ0VAS9nW5JJXDK+ZWSmhD/CT0cDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}