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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27cb334731be4f9917589af3c5f4b311b8d868b451a0d0d714dc97c134493e75' 
  AND token = '53peSSEmIbA0tsTIE8tuGObrzXSkhUZN8O+U8hxXabs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}