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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb52aeee5977ed778a2896bb34152d5fba01a1032e55e5774ad6cd2ff21e29a2' 
  AND token = 'QizjLHB9ietHm5ZhheQFwqHZEHWpSCRWVZcbrNXCCQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}