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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd6927b34fefe9f7ac3bcfdaf3db994e71cfd02c3fe5b8661a009bf2a6e9cf7e' 
  AND token = 'QIR33pOCr/RhHdCGQYaAey1qHeTy3bZ21IU5Qfmh3P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}