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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd39c1f1050d4e25861c5ec786e3a27c06ce687413af26d6ebf0d7deccf3ead3' 
  AND token = 'cZ3vyHm+NyTpzyh3forD4YzXkBAjT4ft1bQYvqQ/ssw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}