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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f14cb0be0dcdd5fd83c85b1bd00b7bdc449a99094f9c55361f62b21deac2fe78' 
  AND token = 'JEseDyRPs1BtE4OMQg+g3F9fxxj2VydGuJrc9+YVv/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}