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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d153220d5aa69e6732674fd4c1f6b2a178cf06ff44a8da3bd126806c69748d' 
  AND token = 'XIPN4lq5DmtcqQR4Nr8NuVC9gtXEU783XpYteB/g8JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}