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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '862a6d3d6ac8b788c89630bb5415388d5ef8af3fe1496a442dd162e778afa8ef' 
  AND token = 'rRkFtl8yRMRkm+ZZiAqBKGOTZkcrCAv55XKIDd+CekM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}