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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5168b0200b2b8b45e35da653c3945ccd521bcef8f2f29575e67c348976367f8f' 
  AND token = '8b9i75LtuLDHQIQc5xO5ehxbUS1JD1usI4NxggPPans=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}