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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d590f0dc25504aca8453dae40c0287ee17a66320630a9e325f69145a20ecc12' 
  AND token = '3ygjaX+Jh8g8Iz7Um+ICAgLsmoLzAd6EDGuzbFNTTik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}