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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77df0cc90fd1b200fcb6e1cb63727056119616cd81e6f57a569843c3ce330bf1' 
  AND token = 'G0yZ77WeSxYOKNM+Yncj5xKnFS5Y7CEfRiVmqcY/byU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}