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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec64324b1e99071dc2c78e339e4847341dad743cc993aa5c58a377ad8f0f3d80' 
  AND token = 'i13YasESXZB/9f5cUxQLqJ0E4rJhZPfom1NMutucWgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}