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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e63f235810e6a66a66ed7e7df0f36574d57397702cf179d85cb7bb4e973bccc' 
  AND token = 'RGKHnnfdZgPc8ScD0QT2kHAhZ1iIioBrETroBMvextE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}