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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fd650fd6a55fcb7c8330c2c020313b025f80196d680cf33ce3c4872a063c8f5' 
  AND token = '8kPa8H2DfAiFvPjuIQmbiIAENA7LBjDBZDbFMUdAgBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}