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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452294efd0400d4d015e7cc9468405358444f92cf9d7028d48b2f5f92acea649' 
  AND token = 'Fwu1icQ9DQZTGS0S9eDflPU8RknSvaz8uzHZUnC/aKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}