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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0fe6efbd7fc56bae94252725057e2df1f529127c7c61ae5b9e602b2f67826c1' 
  AND token = 'Ub2JS4mep+UoC569YI3pjyRFwasGYfdB47A+R8xRHLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}