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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ddc387f7f647c0aef4ad3b51e4ac2045c353699ae3a37c625ea9811d875e28f' 
  AND token = '6d7vlPftd4Zz2Nke3jwUgNLMFMy2E2QnStOB1Xk2kDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}