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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd44ea9db562e7dc06beacb048e0d9fcd28f2ea37a1dd5db4b60f857c39143728' 
  AND token = 'LNsFU7FYGdnFpwczlUKkmlqYDAcVokXI8eo2sK+wFJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}