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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae25fd97c04e30bd7fcebe33e0ad0be8302a1941d4ae692a202a767846a7587f' 
  AND token = 'eV+VqSsS1LuB3Pfc3amuGRLCLP9vmsh/EnQBanV/BII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}