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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb8b50371cde1ea3af954950a0e7a1fab30136707970e5a5cdbeb21b5091d3c5' 
  AND token = 'QX0s6z/dg9QNV8A7IiZHPc0kXlXlvV4KVaEBjXwyEi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}