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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd35b8639bc01c06ef6bc01c0c24dcc7a46c334f23d878285963d0321c5597f05' 
  AND token = 'dOnZsFHyH78xCr4SpEcmAf7RRb6aqyNne4cBo6WA41c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}