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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c82db398c5339b265869cecd88f171c60b371bdb27e8f0d97fd382a765b6aef0' 
  AND token = 'WkXy173SwpAVWxaDPomBQYfkjYyiT6sojzVK5i16zqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}