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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cb6e82e1aac27bfa64fa62d89d1d1918eba23bafda8ce0e6c564f866fd81c6c' 
  AND token = 'aYDl4j6kwSRgxe1nji1mBvhjY+j+qnm3qIyYBicjTEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}