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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9263cd74891862eeff6265c9f0c51d034f74f54e227d8262cbb0a1711dd6688' 
  AND token = 'aaN9wHFLGgmTQoAt6ErsDJoO1iRimgQnEuDRmPmin7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}