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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08cb1d6fb56856d473d091efe215c330725e34959fa6764123eff2f420f3a0bc' 
  AND token = 'b+FNi5BAcw7nrl7I9fdOMZ6h1JVxBiPITLggCAzBL18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}