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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a342f4e40735e78f6aa649c9aa13684312edac10b1807514fa7c045a51d36e' 
  AND token = 'e7NlpX2x2sPx//rhmcpUwAvu4CCpZOFozGiXvpBImog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}