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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '424e846a62ba6c452a61bdab133b93f184a3ced3b86ce8bc46226bd0738e0061' 
  AND token = 'mqxLaoBhpyq0P9iV8CRJwCyQIPhqiXP58PjhAEw+Th0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}